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Published On: Mon, Jun 2nd, 2014

Texas: Variant Creutzfeldt-Jakob Disease death confirmed, infection likely occurred overseas

Laboratory tests have confirmed a diagnosis of variant CJD (a fatal brain disorder) in a patient who recently died in Texas. The confirmation was made when laboratory results from an autopsy of the patient’s brain tested positive for variant CJD, according to a Centers for Disease Control and Prevention news release today.

Variant Creutzfeldt-Jakob disease (vCJD)- photomicrograph of brain tissue reveals the presence of typical amyloid plaques/CDC

Variant Creutzfeldt-Jakob disease (vCJD)- photomicrograph of brain tissue reveals the presence of typical amyloid plaques/CDC

First described in 1996 in the United Kingdom, variant CJD is a rare, degenerative, fatal brain disorder in humans. It is believed to be caused by consumption of products from cows with the disease bovine spongiform encephalopathy (BSE, or “mad cow” disease).

Worldwide, more than 220 variant CJD patients have been reported, with a majority of them in the United Kingdom (177 cases) and France (27 cases). This case is the fourth to be reported in the United States. In each of the three previous cases, infection likely occurred outside the United States, including the United Kingdom (2 cases) and Saudi Arabia (1 case). The history of this fourth patient, including extensive travel to Europe and the Middle East, supports the likelihood that infection occurred outside the United States.

The last case confirmed in the US was in 2007  in a US resident in Virginia who was born and raised in Saudi Arabia and has lived in the United States since late 2005.

CDC assisted the Texas Department of State Health Services (DSHS)’s investigation of this case and will continue to help confirm further details of the patient’s history, including the potential source of infection. There are no Texas public health concerns or threats associated with this case.

A classic form of CJD, which is not caused by the BSE agent, occurs worldwide, including in the United States. Annually, for every 1 million people in the United States, 1 to 2 develops classic CJD. More information about variant CJD, including how it differs from classic CJD, is available in the Variant Creutzfeldt-Jakob Disease Fact Sheet.

Variant CJD  has different clinical and pathologic characteristics from classic CJD. Each disease also has a particular genetic profile of the prion protein gene.  The median age at death for vCJD patients is 28 years, compared with 68 years for patients with classic CJD. The median duration of illness for vCJD is 14 months, compared to 5 months for classic CJD.

Clinical and Pathologic Characteristics
Distinguishing Classic CJD from variant CJD
Characteristic Classic CJD Variant CJD
Median age at death 68 years 28 years
Median duration of illness 4-5 months 13-14 months
Clinical signs and symptoms Dementia; early neurologic signs Prominent psychiatric/behavioral symptoms; painful dyesthesiasis; delayed neurologic signs
Periodic sharp waves on electroencephalogram Often present Often absent
“Pulvinar sign” on MRI* Not reported Present in >75% of cases
Presence of “florid plaques” on neuropathology Rare or absent Present in large numbers
Immunohitochemical analysis of brain tissue Variable accumulation Marked accumulation of protease-resistance prion protein
Presence of agent in lymphoid tissue Not readily detected Readily detected
Increased glycoform ratio on immunoblot analysis of protease-resistance prion protein Not reported Marked accumulation of protease-resistance prion protein
Source: Adapted from Belay E., Schonberger L. Variant Creutzfeldt-Jakob Disease and Bovine Spongiform Encephalopathy. Clin Lab Med 2002;22:849-62.

*An abnormal signal in the posterior thalami on T2- and diffusion-weighted images and fluid-attenuated inversion recovery sequences on brain magnetic resonance imaging (MRI); in the appropriate clinical context, this signal is highly specific for vCJD.

About the Author

- Writer, Co-Founder and Executive Editor of The Global Dispatch. Robert has been covering news in the areas of health, world news and politics for a variety of online news sources. He is also the Editor-in-Chief of the website, Outbreak News Today and hosts the Outbreak News This Week Radio Show on http://1380thebiz.com/ Robert is politically Independent and a born again Christian Follow @bactiman63

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  1. o.k. folks, were still waiting for a report about this poor mans case history. what gives $$$

    Thursday, September 18, 2014

    Development of Dose-Response Models of Creutzfeldt-Jakob Disease Infection in Nonhuman Primates for Assessing the Risk of Transfusion-Transmitted variant Creutzfeldt-Jakob Disease

    http://vcjdtransfusion.blogspot.com/2014/09/development-of-dose-response-models-of.html

  2. […] and laboratory evidence for a causal association between a new human prion disease called variant Creutzfeldt-Jakob disease (vCJD) that was first reported from the United Kingdom in 1996 and the BSE outbreak in cattle. For more […]

  3. […] Texas: Variant Creutzfeldt-Jakob Disease death confirmed, infection likely occurred overseas – The G… […]

  4. CJD NE TEXAS CLUSTER

    Creutzfeldt-Jakob Disease in Northeast Texas

    J.A. Rawlings,*1 K.A. Hendricks1, O.M. Nuno1, D.A. Brown1, D.A. Evans2, Texas Department of Health, 1Austin and 2Tyler, Texas Creutzfeldt-Jacob Disease (CJD), a transmissible spongiform encephalopathy, is caused by prions composed of proteinaceous material devoid of nucleic acid. CJD occurs sporadically (generally 1 case/1,000,000 population per year) in older patients (average age of 65) and is characterized by rapidly progressive dementia, accompanied by severe muscle spasms and incoordination. Death usually occurs within 3 to 12 months (average 7 months). CJD activity in Texas, which has a population of nearly 19 million, appeared to be typical. The statewide death rate for 1995 and 1996 was just under 1/1,000,000. In April of 1997, the Texas Department of Health became aware of an increased number of possible CJD cases in a 23-county area of NE Texas with a population of just over one million. After review of medical and pathology records, four patients were identified with definite classic CJD and three were identified with probable CJD. Dates of death for the eight patients were from April, 1996 through mid-July 1997. The patients were from 46 through 65 years of age; four were male and three were female. A case-control study to identify risks for CJD in NE Texas has been initiated. http://www.jifsan.umd.edu/tse/Rawlings.htm

    Monday, March 29, 2010

    CJD TEXAS 38 YEAR OLD FEMALE WORKED SLAUGHTERING CATTLE EXPOSED TO BRAIN AND SPINAL CORD MATTER

    URGENT, PLEASE NOTE ;

    >>> Up until about 6 years ago, the pt worked at Tyson foods where she worked on the assembly line, slaughtering cattle and preparing them for packaging. She was exposed to brain and spinal cord matter when she would euthanize the cattle. <<>> Up until about 6 years ago, the pt worked at Tyson foods where she worked on the assembly line, slaughtering cattle and preparing them for packaging. She was exposed to brain and spinal cord matter when she would euthanize the cattle. <<<

    Irma Linda Andablo CJD Victim, she died at 38 years old on February 6, 2010 in Mesquite Texas.

    http://cjdtexas.blogspot.com/2010/03/cjd-texas-38-year-old-female-worked.html

    Singeltary family experience with CJD Listserve 22 May 98

    Hello, my name is Terry S. Singeltary Sr. and on 12-14-97 my mother died of heidenhan variant CJD, she died a very hidious death. Next, on 12-14-96 exactly one year earlier,my neighbors' mother died from C.J.D. Ii have autopsies to confirm both cases.not to long after my mother had passed away,my neighbor called me and said that I needed to see something. He had been going through a box that he had come across of his mothers. Inside was a bottle of nutritional supplements called IPLEX; INGREDIANTS;VACUUM DRIED BOVINE BRAIN,BONE MEAL,BOVINE EYE,VEAL BONE,BOVINE LIVER POWDER,BOVINE ADRENAL,VACUUM DRIED BOVINE KIDNEY,AND VACUUM DRIED PORCINE STOMACH, it's a cow in a pill. Now this woman taking these pills,died of C.J.D.there was a big article in the Galveston Daily News about all of this. I called the Texas Dept. Of Health and they came and got the pills the next day. Julie Rawlings at the texas dept. of health told me last week that the manufacturer has clammed up on them and will not cooperate anymore. They are referring all matters to their lawyers now.how can this be? Why doesn't the federal government intervEne?

    Since the story came out in the galv. news on april 27,1998.a girl called me and told me of her father dying in late 94 or early 95 of C.J.D. in galveston. She told me that my mothers doctor was also her fathers doctor.now my mothers doctor would always mention the OTHER CASE but that's as far as it went.NOW i know why,her father was a BUTCHER AT A MEAT MARKET IN GALVESTON UNTIL HE RETIRED.

    Makes me wonder? Did mom ever eat any beef that had come from that meat market in the last 30 or 40 years? MADCOW is here and you can call it whatever you want to. I saw it, my mother died from it. At times she would jerk so bad it would take 3 of us to hold her down.10 weeks start to finish,and she was gone.this disease that they claim is a different disease in younger folks (nvcjd) is the same damn thing. Just because it last longer and the plaques are a little more extreme,could it not be just a more extreme case of C.J.D. any young person with any disease will last longer than a older person with the same disease, because their body and organs are much younger and healthier.

    The manufacturer of IPLEX is Standard Process Inc., Palmyra, Wisconsin.1-800-558-8740. I hope you find some interest in this.if you need more details,please don't hesitate to contact me."

    With thanks,

    Terry S. Singeltary

    Texas cluster web site 21 May 98 Mark V. Gregg 512-458-7677 fax 512-458-7616 Director, Public Health Professional Education Texas Department of Health 1100 West 49th Street T-803 Austin, Texas 78756

    "We've developed a CJD Web page here at the Texas Department of Health. In addition to some general information, the page links to the CDC's CJD page as well as a 1996 issue of our biweekly morbidity and mortality newsletter, the Disease Prevention News, which is also available on the Web. Our Infectious Disease Epidemiology and Surveillance (IDEAS) Division is currently investigating what we believe to be a cluster of CJD in a small area in East Texas. The Division's number is on the Web page if you wanted to follow up with specifics."

    http://www.mad-cow.org/mid_may98.html#aaa

    http://www.fortunecity.com/healthclub/cpr/798/terry.htm

    North American Equity Research

    New York

    13 January 2004

    BSE (Mad Cow) Update:

    Do Reports of sCJD Clusters Matter?

    SNIP…SEE FULL TEXT ;

    http://cjdtexas.blogspot.com/2007/12/creutzfeldt-jakob-disease-surveillance.html

    GLOBAL CLUSTERS OF CJD

    http://creutzfeldt-jakob-disease.blogspot.com/2010/07/global-clusters-of-creutzfeldt-jakob.html

    Tuesday, July 29, 2008

    Heidenhain Variant Creutzfeldt Jakob Disease Case Report

    snip…

    Heidenhain Variant Creutzfeldt Jakob Disease autopsy case report 'MOM'

    DIVISION OF NEUROPATHOLOGY University of Texas Medical Branch 114 McCullough Bldg. Galveston, Texas 77555-0785

    FAX COVER SHEET

    DATE: 4-23-98

    TO: Mr. Terry Singeltary @ ——-

    FROM: Gerald Campbell

    FAX: (409) 772-5315 PHONE: (409) 772-2881

    Number of Pages (including cover sheet):

    Message:

    *CONFIDENTIALITY NOTICE*

    This document accompanying this transmission contains confidential information belonging to the sender that is legally privileged. This information is intended only for the use of the individual or entry names above. If you are not the intended recipient, you are hereby notified that any disclosure, copying distribution, or the taking of any action in reliances on the contents of this telefaxed information is strictly prohibited. If you received this telefax in error, please notify us by telephone immediately to arrange for return of the original documents. ————————– Patient Account: 90000014-518 Med. Rec. No.: (0160)118511Q Patient Name: POULTER, BARBARA Age: 63 YRS DOB: 10/17/34 Sex: F Admitting Race: C

    Attending Dr.: Date / Time Admitted : 12/14/97 1228 Copies to:

    UTMB University of Texas Medical Branch Galveston, Texas 77555-0543 (409) 772-1238 Fax (409) 772-5683 Pathology Report

    FINAL AUTOPSY DIAGNOSIS Autopsy' Office (409)772-2858

    Autopsy NO.: AU-97-00435

    AUTOPSY INFORMATION: Occupation: Unknown Birthplace: Unknown Residence: Crystal Beach Date/Time of Death: 12/14/97 13:30 Date/Time of Autopsy: 12/15/97 15:00 Pathologist/Resident: Pencil/Fernandez Service: Private Restriction: Brain only

    FINAL AUTOPSY DIAGNOSIS

    I. Brain: Creutzfeldt-Jakob disease, Heidenhain variant.

    snip…see full text ;

    http://creutzfeldt-jakob-disease.blogspot.com/2008/07/heidenhain-variant-creutzfeldt-jakob.html

    Mad cow disease: Could it be here?

    Man's stubborn crusade attracts experts' notice By Carol Christian | August 5, 2001

    http://www.chron.com/news/houston-texas/article/Mad-cow-disease-Could-it-be-here-2042860.php

    remember what deep throat told me long ago ;

    DEEP THROAT TO TSS 2000-2001 (take these old snips of emails with how ever many grains of salt you wish. …tss)

    DEEP THROAT TO TSS 2000-2001 (take these old snips of emails with how ever many grains of salt you wish. …tss)

    The most frightening thing I have read all day is the report of Gambetti's finding of a new strain of sporadic cjd in young people…Dear God, what in the name of all that is holy is that!!! If the US has different strains of scrapie…..why????than the UK…then would the same mechanisms that make different strains of scrapie here make different strains of BSE…if the patterns are different in sheep and mice for scrapie…..could not the BSE be different in the cattle, in the mink, in the humans…….I really think the slides or tissues and everything from these young people with the new strain of sporadic cjd should be put up to be analyzed by many, many experts in cjd……..bse…..scrapie Scrape the damn slide and put it into mice…..wait…..chop up the mouse brain and and spinal cord……..put into some more mice…..dammit amplify the thing and start the damned research…..This is NOT rocket science…we need to use what we know and get off our butts and move….the whining about how long everything takes…..well it takes a whole lot longer if you whine for a year and then start the research!!! Not sure where I read this but it was a recent press release or something like that: I thought I would fall out of my chair when I read about how there was no worry about infectivity from a histopath slide or tissues because they are preserved in formic acid, or formalin or formaldehyde…..for God's sake…….. Ask any pathologist in the UK what the brain tissues in the formalin looks like after a year…….it is a big fat sponge…the agent continues to eat the brain ……you can't make slides anymore because the agent has never stopped……..and the old slides that are stained with Hemolysin and Eosin……they get holier and holier and degenerate and continue…what you looked at 6 months ago is not there……..Gambetti better be photographing every damned thing he is looking at…..

    Okay, you need to know. You don't need to pass it on as nothing will come of it and there is not a damned thing anyone can do about it. Don't even hint at it as it will be denied and laughed at………. USDA is gonna do as little as possible until there is actually a human case in the USA of the nvcjd……..if you want to move this thing along and shake the earth….then we gotta get the victims families to make sure whoever is doing the autopsy is credible, trustworthy, and a saint with the courage of Joan of Arc……..I am not kidding!!!! so, unless we get a human death from EXACTLY the same form with EXACTLY the same histopath lesions as seen in the UK nvcjd……..forget any action……..it is ALL gonna be sporadic!!!

    And, if there is a case…….there is gonna be every effort to link it to international travel, international food, etc. etc. etc. etc. etc. They will go so far as to find out if a sex partner had ever traveled to the UK/europe, etc. etc. …. It is gonna be a long, lonely, dangerous twisted journey to the truth. They have all the cards, all the money, and are willing to threaten and carry out those threats….and this may be their biggest downfall…

    Thanks as always for your help. (Recently had a very startling revelation from a rather senior person in government here……….knocked me out of my chair……..you must keep pushing. If I was a power person….I would be demanding that there be a least a million bovine tested as soon as possible and agressively seeking this disease. The big players are coming out of the woodwork as there is money to be made!!! In short: "FIRE AT WILL"!!! for the very dumb….who's "will"! "Will be the burden to bare if there is any coverup!"

    again it was said years ago and it should be taken seriously….BSE will NEVER be found in the US! As for the BSE conference call…I think you did a great service to freedom of information and making some people feign integrity…I find it scary to see that most of the "experts" are employed by the federal government or are supported on the "teat" of federal funds. A scary picture! I hope there is a confidential panel organized by the new government to really investigate this thing.

    You need to watch your back……..but keep picking at them…….like a buzzard to the bone…you just may get to the truth!!! (You probably have more support than you know. Too many people are afraid to show you or let anyone else know. I have heard a few things myself… you ask the questions that everyone else is too afraid to ask.)

    END…TSS

    we get them young cases of tse prion disease in Texas, that is not related to anything $$$ money and politics will buy anything, especially junk science… sporadic ffi and sporadic gss ;

    NOT THIS CASE !!! but another one a while back in Texas…see ;

    We report a case of a 33-year-old female who died of a prion disease for whom the diagnosis of sFI or FFI was not considered clinically. Following death of this patient, an interview with a close family member indicated the patient's illness included a major change in her sleep pattern, corroborating the reported autopsy diagnosis of sFI.

    http://creutzfeldt-jakob-disease.blogspot.com/2013/10/cjd-tse-prion-disease-cases-in-texas-by.html

    sporadic FFI or nvCJD Texas style ???

    http://creutzfeldt-jakob-disease.blogspot.com/2011/11/case-report-sporadic-fatal-insomnia-in.html

    Creutzfeldt-Jakob Disease Surveillance in Texas

    http://cjdtexas.blogspot.com/2010/06/usa-cases-of-dpcjd-rising-with-24-cases.html

    Sunday, July 11, 2010

    CJD or prion disease 2 CASES McLennan County Texas population 230,213 both cases in their 40s

    http://creutzfeldt-jakob-disease.blogspot.com/2010/07/cjd-2-cases-mclennan-county-texas.html

    http://cjdtexas.blogspot.com/

    2009 UPDATE ON ALABAMA AND TEXAS MAD COWS 2005 and 2006

    http://bse-atypical.blogspot.com/2006/08/bse-atypical-texas-and-alabama-update.html

    Monday, May 19, 2014

    Variant CJD: 18 years of research and surveillance

    http://vcjd.blogspot.com/2014/05/variant-cjd-18-years-of-research-and.html

    kind regards, terry

  5. […] Source: http://www.theglobaldispatch.com/texas-variant-creutzfeldt-jakob-disease-death-confirmed-infection-l… […]

  6. Confirmed Variant CJD Case in Texas

    Lab tests have confirmed a diagnosis of variant Creutzfeldt-Jakob Disease (CJD) in a patient who recently died in Texas. Variant CJD is a rare, fatal brain disorder, first described in 1996 in the United Kingdom and associated with beef consumption overseas.

    This is the fourth case ever reported in the United States. In each of the three previous cases, infection likely occurred outside the United States, including the United Kingdom and Saudi Arabia. The history of this fourth patient includes extensive travel to Europe and the Middle East, and infection likely occurred outside the United States. The CDC and DSHS continue to investigate the case.

    There are no Texas public health concerns or threats associated with this case.

    CDC Confirmation Information: http://www.cdc.gov/ncidod/dvrd/vcjd/other/confirmed-case-in-texas.htm

    CDC Fact Sheet: http://www.cdc.gov/ncidod/dvrd/vcjd/factsheet_nvcjd.htm

    Texas CJD Information: http://www.dshs.state.tx.us/idcu/disease/creutzfeldt-jakob/

    http://www.dshs.state.tx.us/

    Saturday, April 19, 2014

    *** Exploring the zoonotic potential of animal prion diseases: In vivo and in vitro approaches ***

    *** These results would seem to suggest that CWD does indeed have zoonotic potential, at least as judged by the compatibility of CWD prions and their human PrPC target. Furthermore, extrapolation from this simple in vitro assay suggests that if zoonotic CWD occurred, it would most likely effect those of the PRNP codon 129-MM genotype and that the PrPres type would be similar to that found in the most common subtype of sCJD (MM1).

    http://transmissiblespongiformencephalopathy.blogspot.com/2014/04/exploring-zoonotic-potential-of-animal.html

    Friday, April 25, 2014

    Accuracy of administrative diagnostic data for pathologically confirmed cases of Creutzfeldt-Jakob disease in Massachusetts, 2000-2008

    Article in Press

    http://creutzfeldt-jakob-disease.blogspot.com/2014/04/accuracy-of-administrative-diagnostic.html

    CANADA SEE STEADY INCREASE OF THE SPORADIC CJD’S AND THE VPSPR’S (sporadic CJD’s). …tss

    PLEASE NOTE, type determination pending Creutzfeldt Jakob Disease (tdpCJD) in Canada is also on a steady increase.

    please see ;

    > 3. Final classification of 50 cases from 2009, 2010, 2011 and 2012 is pending.

    CJD Deaths Reported by CJDSS1, 1994-20122

    CJD Deaths Reported by CJDSS1, 1994-20122

    As of May 31, 2012

    http://www.phac-aspc.gc.ca/hcai-iamss/cjd-mcj/cjdss-ssmcj/pdf/stats_0512-eng.pdf

    http://creutzfeldt-jakob-disease.blogspot.com/2012/08/cjd-case-in-saint-john-prompts-letter.html

    SEE DECEMBER 2012 CANADA

    http://www.phac-aspc.gc.ca/hcai-iamss/cjd-mcj/cjdss-ssmcj/stats-eng.php#canada

    USA SEE STEADY INCREASE OF THE SPORADIC CJD’S AND THE VPSPR’S (sporadic CJD’s). …tss

    National Prion Disease Pathology Surveillance Center

    Cases Examined1

    (May 18, 2012)

    5 Includes 14 cases in which the diagnosis is pending, and 18 inconclusive cases;

    6 Includes 17 (16 from 2012) cases with type determination pending in which the diagnosis of vCJD has been excluded. The Sporadic cases include 16 cases of sporadic Fatal Insomnia (sFI) and 42 cases of Variably Protease-Sensitive Prionopathy (VPSPr) and 2118 cases of sporadic Creutzfeldt-Jakob disease (sCJD).

    Rev 5/18/2012

    http://www.cjdsurveillance.com/pdf/case-table.pdf

    > 6 Includes

    > 17 (16 from 2012) cases with type determination pending in which the diagnosis of vCJD has been excluded.

    > The Sporadic cases include 16 cases of sporadic Fatal Insomnia (sFI) and 42 cases of Variably Protease-Sensitive Prionopathy (VPSPr) and 2118 cases of sporadic Creutzfeldt-Jakob disease (sCJD).

    WELL, it seems the USA mad cow strains in humans classified as type determination pending tdpCJD, VPSPr, sFFI, and sCJD) have steadily increased over the years, and the same old song and dance continues with sporadic CJD cases $$$

    http://creutzfeldt-jakob-disease.blogspot.com/2012/06/creutzfeldt-jakob-disease-human-tse.html

    Creutzfeldt-Jakob Disease CJD cases rising North America updated report August 2013

    *** Creutzfeldt-Jakob Disease CJD cases rising North America with Canada seeing an extreme increase of 48% between 2008 and 2010 ***

    http://creutzfeldt-jakob-disease.blogspot.com/2013/08/creutzfeldt-jakob-disease-cjd-cases.html

    Sunday, October 13, 2013

    *** CJD TSE Prion Disease Cases in Texas by Year, 2003-2012

    http://creutzfeldt-jakob-disease.blogspot.com/2013/10/cjd-tse-prion-disease-cases-in-texas-by.html

    Tuesday, April 01, 2014

    *** Questions linger in U.S. CJD cases 2005, and still do in 2014

    http://creutzfeldt-jakob-disease.blogspot.com/2014/04/questions-linger-in-us-cjd-cases-2005.html

    Sunday, March 09, 2014

    A Creutzfeldt-Jakob Disease (CJD) Lookback Study: Assessing the Risk of Blood Borne Transmission of Classic Forms of Creutzfeldt-Jakob Disease

    *** FDA TSEAC CIRCUS AND TRAVELING ROAD SHOW FOR THE TSE PRION DISEASES

    http://creutzfeldt-jakob-disease.blogspot.com/2014/03/a-creutzfeldt-jakob-disease-cjd.html

    Sunday, April 06, 2014

    *** SPORADIC CJD and the potential for zoonotic transmission there from, either directly or indirectly via friendly fire iatrogenic mode, evidence to date

    http://creutzfeldt-jakob-disease.blogspot.com/2014/04/sporadic-cjd-and-potential-for-zoonotic.html

    Wednesday, December 11, 2013

    *** Detection of Infectivity in Blood of Persons with Variant and Sporadic Creutzfeldt-Jakob Disease ***

    http://creutzfeldt-jakob-disease.blogspot.com/2013/12/detection-of-infectivity-in-blood-of.html

    Sunday, April 06, 2014

    SPORADIC CJD and the potential for zoonotic transmission there from, either directly or indirectly via friendly fire iatrogenic mode, evidence to date

    http://creutzfeldt-jakob-disease.blogspot.com/2014/04/sporadic-cjd-and-potential-for-zoonotic.html

    Friday, January 10, 2014

    vpspr, sgss, sffi, TSE, an iatrogenic by-product of gss, ffi, familial type prion disease, what it ???

    http://transmissiblespongiformencephalopathy.blogspot.com/2014/01/vpspr-sgss-sffi-tse-iatrogenic-by.html

    Monday, May 19, 2014

    Variant CJD: 18 years of research and surveillance

    http://vcjd.blogspot.com/2014/05/variant-cjd-18-years-of-research-and.html

    remember, the sporadic cjd i.e. 85%+ of all human tse prion disease, has now been linked to ;

    I would just like to add, that 85%+ of all human TSE prion disease, i.e. sporadic CJD, is not a single strain, and has never been proven to be a spontaneous mutation and or sporadic event caused by _nothing_ environmentally. no where in science has this ever been proven, as the defining cause of all human sporadic CJD cases. it’s a hypothesis, it’s a myth. there are many, many, routes and sources of the TSE prion disease in North America. sporadic CJD simply means one thing, and remember this. UNKNOWN !

    ——– Original Message ——–

    Subject: re-BSE prions propagate as either variant CJD-like or sporadic CJD

    Date: Thu, 28 Nov 2002 10:23:43 -0000

    From: “Asante, Emmanuel A” [email protected]

    To: “‘[email protected]'” [email protected]

    Dear Terry,

    I have been asked by Professor Collinge to respond to your request. I am a Senior Scientist in the MRC Prion Unit and the lead author on the paper. I have attached a pdf copy of the paper for your attention.

    Thank you for your interest in the paper.

    In respect of your first question, the simple answer is, ***yes. As you will find in the paper, we have managed to associate the alternate phenotype to type 2 PrPSc, the commonest sporadic CJD. It is too early to be able to claim any further sub-classification in respect of Heidenhain variant CJD or Vicky Rimmer’s version. It will take further studies, which are on-going, to establish if there are sub-types to our initial finding which we are now reporting. The main point of the paper is that, as well as leading to the expected new variant CJD phenotype, BSE transmission to the 129-methionine genotype can lead to an alternate phenotype which is indistinguishable from type 2 PrPSc.

    I hope reading the paper will enlighten you more on the subject. If I can be of any further assistance please to not hesitate to ask. Best wishes.

    Emmanuel Asante

    <>

    ____________________________________

    Dr. Emmanuel A Asante MRC Prion Unit & Neurogenetics Dept. Imperial College School of Medicine (St. Mary’s) Norfolk Place, LONDON W2 1PG Tel: +44 (0)20 7594 3794 Fax: +44 (0)20 7706 3272 email: [email protected] (until 9/12/02) New e-mail: [email protected] (active from now)

    ____________________________________

    Thursday, August 12, 2010

    Seven main threats for the future linked to prions

    First threat

    The TSE road map defining the evolution of European policy for protection against prion diseases is based on a certain numbers of hypotheses some of which may turn out to be erroneous. In particular, a form of BSE (called atypical Bovine Spongiform Encephalopathy), recently identified by systematic testing in aged cattle without clinical signs, may be the origin of classical BSE and thus potentially constitute a reservoir, which may be impossible to eradicate if a sporadic origin is confirmed.

    ***Also, a link is suspected between atypical BSE and some apparently sporadic cases of Creutzfeldt-Jakob disease in humans. These atypical BSE cases constitute an unforeseen first threat that could sharply modify the European approach to prion diseases.

    Second threat

    snip…

    http://www.neuroprion.org/en/np-neuroprion.html

    Monday, October 10, 2011

    EFSA Journal 2011 The European Response to BSE: A Success Story

    snip…

    EFSA and the European Centre for Disease Prevention and Control (ECDC) recently delivered a scientific opinion on any possible epidemiological or molecular association between TSEs in animals and humans (EFSA Panel on Biological Hazards (BIOHAZ) and ECDC, 2011). This opinion confirmed Classical BSE prions as the only TSE agents demonstrated to be zoonotic so far

    *** but the possibility that a small proportion of human cases so far classified as “sporadic” CJD are of zoonotic origin could not be excluded. Moreover, transmission experiments to non-human primates suggest that some TSE agents in addition to Classical BSE prions in cattle (namely L-type Atypical BSE, Classical BSE in sheep, transmissible mink encephalopathy (TME) and chronic wasting disease (CWD) agents) might have zoonotic potential.

    snip…

    http://www.efsa.europa.eu/en/efsajournal/pub/e991.htm?emt=1

    http://www.efsa.europa.eu/en/efsajournal/doc/e991.pdf

    To date the OIE/WAHO assumes that the human and animal health standards set out in the BSE chapter for classical BSE (C-Type) applies to all forms of BSE which include the H-type and L-type atypical forms. This assumption is scientifically not completely justified and accumulating evidence suggests that this may in fact not be the case. Molecular characterization and the spatial distribution pattern of histopathologic lesions and immunohistochemistry (IHC) signals are used to identify and characterize atypical BSE. Both the L-type and H-type atypical cases display significant differences in the conformation and spatial accumulation of the disease associated prion protein (PrPSc) in brains of afflicted cattle. Transmission studies in bovine transgenic and wild type mouse models support that the atypical BSE types might be unique strains because they have different incubation times and lesion profiles when compared to C-type BSE. When L-type BSE was inoculated into ovine transgenic mice and Syrian hamster the resulting molecular fingerprint had changed, either in the first or a subsequent passage, from L-type into C-type BSE.

    ***In addition, non-human primates are specifically susceptible for atypical BSE as demonstrated by an approximately 50% shortened incubation time for L-type BSE as compared to C-type. Considering the current scientific information available, it cannot be assumed that these different BSE types pose the same human health risks as C-type BSE or that these risks are mitigated by the same protective measures.

    http://www.prionetcanada.ca/detail.aspx?menu=5&dt=293380&app=93&cat1=387&tp=20&lk=no&cat2

    Monday, May 19, 2014

    Variant CJD: 18 years of research and surveillance

    http://vcjd.blogspot.com/2014/05/variant-cjd-18-years-of-research-and.html

    Discussion: The C, L and H type BSE cases in Canada exhibit molecular characteristics similar to those described for classical and atypical BSE cases from Europe and Japan. *** This supports the theory that the importation of BSE contaminated feedstuff is the source of C-type BSE in Canada. *** It also suggests a similar cause or source for atypical BSE in these countries. ***

    see page 176 of 201 pages…tss

    http://www.neuroprion.org/resources/pdf_docs/conferences/prion2009/prion2009_bookofabstracts.pdf

    *** Singeltary reply ; Molecular, Biochemical and Genetic Characteristics of BSE in Canada Singeltary reply ;

    http://www.plosone.org/annotation/listThread.action;jsessionid=635CE9094E0EA15D5362B7D7B809448C?root=7143

    Sunday, December 15, 2013

    *** FDA PART 589 — SUBSTANCES PROHIBITED FROM USE IN ANIMAL FOOD OR FEED VIOLATIONS OFFICIAL ACTION INDICATED OIA UPDATE DECEMBER 2013 UPDATE

    http://madcowusda.blogspot.com/2013/12/fda-part-589-substances-prohibited-from.html

    2004, highly suspect stumbling and staggering mad cow reported, however, NO TESTING DONE, ON ORDERS FROM AUSTIN $

    May 4, 2004

    Statement on Texas Cow With Central Nervous System Symptoms

    On Friday, April 30th, the Food and Drug Administration learned that a cow with central nervous system symptoms had been killed and shipped to a processor for rendering into animal protein for use in animal feed.

    FDA, which is responsible for the safety of animal feed, immediately began an investigation. On Friday and throughout the weekend, FDA investigators inspected the slaughterhouse, the rendering facility, the farm where the animal came from, and the processor that initially received the cow from the slaughterhouse.

    FDA’s investigation showed that the animal in question had already been rendered into “meat and bone meal” (a type of protein animal feed). Over the weekend FDA was able to track down all the implicated material. That material is being held by the firm, which is cooperating fully with FDA.

    Cattle with central nervous system symptoms are of particular interest because cattle with bovine spongiform encephalopathy or BSE, also known as “mad cow disease,” can exhibit such symptoms. In this case, there is no way now to test for BSE. But even if the cow had BSE, FDA’s animal feed rule would prohibit the feeding of its rendered protein to other ruminant animals (e.g., cows, goats, sheep, bison)…

    http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/2004/ucm108292.htm

    USDA regulations, any cow that exhibits signs of central nervous system (CNS)

    According to a 1997 Animal and Plant Health Inspection Service (NHIS) Memorandum, brain samples all of such animals should be sent for BSE testing.2 The memorandum notes that “it is essential that brain specimens be collected from adult cattle condemned for CNS signs as part of our national surveillance of BSE.”

    The cow slaughtered at the Lone Star Beef slaughterhouse last week staggered and fell, and was condemned ante mortem by FSIS personnel.4 Despite a request from APHIS personnel at the plant to conduct BSE testing, however, an APHIS supervisor in Austin reportedly refused the test and instructed the plant to send the carcass for rendering.5

    May 13,2004

    Page 2

    snip…

    The cow slaughtered at the Lone Star Beef slaughterhouse last week staggered and fell, and was condemned ante mortem by FSIS personnel.4 Despite a request from APHIS personnel at the plant to conduct BSE testing, however, an APHIS supervisor in Austin reportedly refused the test and instructed the plant to send the carcass for rendering.5

    This sequence of events is troubling, and it raises the question of whether this is an isolated incident. In 1997, USDA noted a major gap between the number of cattle condemned for CNS symptoms and the number of these cows actually tested for mad cow disease. The Department found:

    http://democrats.oversight.house.gov/images/stories/documents/20040607142914-86912.pdf

    ——– Original Message ——–

    Subject: re-USDA’s surveillance plan for BSE aka mad cow disease

    Date: Mon, 02 May 2005 16:59:07 -0500

    From: “Terry S. Singeltary Sr.”

    To: [email protected], [email protected], [email protected]

    Greetings Honorable Paul Feeney, Keith Arnold, and William Busbyet al at OIG, ……………

    snip…

    There will be several more emails of my research to follow. I respectfully request a full inquiry into the cover-up of TSEs in the United States of America over the past 30 years. I would be happy to testify…

    Thank you, I am sincerely, Terry S. Singeltary Sr. P.O. Box 42 Bacliff, Texas USA 77518 xxx xxx xxxx

    Date: June 14, 2005 at 1:46 pm PST In

    Reply to: Re: Transcript Ag. Secretary Mike Johanns and Dr. John Clifford, Regarding further analysis of BSE Inconclusive Test Results posted by TSS on June 13, 2005 at 7:33 pm:

    Secretary of Agriculture Ann M. Veneman resigns Nov 15 2004, three days later inclusive Mad Cow is announced. June 7th 2005 Bill Hawks Under Secretary for Marketing and Regulatory Programs resigns. Three days later same mad cow found in November turns out to be positive. Both resignation are unexpected. just pondering… TSS

    MAD COW IN TEXAS NOVEMBER 2004. …TSS

    ——– Original Message ——–

    Director, Public Information Carla Everett [email protected]

    Subject: Re: BSE ‘INCONCLUSIVE’ COW from TEXAS ???

    Date: Mon, 22 Nov 2004 17:12:15 –0600

    From: “Terry S. Singeltary Sr.”

    To: Carla Everett References:

    Greetings Carla,still hear a rumor;

    Texas single beef cow not born in Canada no beef entered the food chain?

    and i see the TEXAS department of animal health is ramping up forsomething, but they forgot a url for update?I HAVE NO ACTUAL CONFIRMATION YET…can you confirm???

    terry

    ——– Original Message ——–

    Subject: Re: BSE ‘INCONCLUSIVE’ COW from TEXAS ???

    Date: Fri, 19 Nov 2004 11:38:21 –0600

    From: Carla Everett

    To: “Terry S. Singeltary Sr.” References:

    The USDA has made a statement, and we are referring all callers to the USDA web site. We have no information about the animal being in Texas. Carla At 09:44 AM 11/19/2004, you wrote:>Greetings Carla,>>i am getting unsubstantiated claims of this BSE ‘inconclusive’ cow is from>TEXAS. can you comment on this either way please?>>

    thank you,>

    Terry S. Singeltary Sr.>>

    ——– Original Message ——–

    Subject: Re: BSE ‘INCONCLUSIVE’ COW from TEXAS ???

    Date: Mon, 22 Nov 2004 18:33:20 -0600 From: Carla Everett

    To: “Terry S. Singeltary Sr.”

    References: …snip tss

    our computer department was working on a place holder we could post USDA’s announcement of any results. There are no results to be announced tonight by NVSL, so we are back in a waiting mode and will post the USDA announcement when we hear something. At 06:05 PM 11/22/2004,

    you wrote:

    >why was the announcement on your TAHC site removed?

    >>Bovine Spongiform Encephalopathy:

    >November 22: Press Release title here

    >>star image More BSE information

    >>>>terry

    >>Carla Everett wrote:

    >>>no confirmation on the U.S.’ inconclusive test…

    >>no confirmation on location of animal.>>>>>>

    ==========================

    ——– Original Message ——–

    Director, Public Information Carla Everett [email protected]

    Subject: Re: BSE ‘INCONCLUSIVE’ COW from TEXAS ???

    Date: Mon, 22 Nov 2004 17:12:15 –0600

    From: “Terry S. Singeltary Sr.”

    To: Carla Everett References:

    Greetings Carla, still hear a rumor;

    Texas single beef cow not born in Canada no beef entered the food chain?

    and i see the TEXAS department of animal health is ramping up forsomething, but they forgot a url for update?I HAVE NO ACTUAL CONFIRMATION YET…can you confirm???

    terry

    ==============================

    http://madcowusda.blogspot.com/2012/06/johanns-introduces-legislation-banning.html

    http://madcowusda.blogspot.com/2012_06_01_archive.html

    USDA did not test possible mad cows

    By Steve Mitchell

    United Press International

    Published 6/8/2004 9:30 PM

    WASHINGTON, June 8 (UPI) — The U.S. Department of Agriculture claims ittested 500 cows with signs of a brain disorder for mad cow disease last year, but agency documents obtained by United Press International show the agency tested only half that number.

    http://madcowtesting.blogspot.com/2007/10/bse-base-mad-cow-testing-texas-usa-and.html

    http://www.usda.gov/oig/webdocs/50601-10-KC.pdf

    “These 9,200 cases were different because brain tissue samples were preserved with formalin, which makes them suitable for only one type of test–immunohistochemistry, or IHC.”

    THIS WAS DONE FOR A REASON!

    THE IHC test has been proven to be the LEAST LIKELY to detect BSE/TSE in the bovine, and these were probably from the most high risk cattle pool, the ones the USDA et al, SHOULD have been testing. …TSS

    TEXAS 2ND MAD COW THAT WAS COVERED UP, AFTER AN ACT OF CONGRESS, AND CALLS FROM TSE PRION SCIENTIST AROUND THE GLOBE, THIS 2ND MAD COW IN TEXAS WAS CONFIRMED

    THE USDA MAD COW FOLLIES POSITIVE TEST COVER UP

    JOHANNS SECRET POSTIVE MAD COW TEST THAT WERE IGNORED

    OIG AND THE HONORABLE FONG CONFIRMS TEXAS MAD AFTER AN ACT OF CONGRESS 7 MONTHS LATER

    TEXAS MAD COW

    THEY DID FINALLY TEST AFTER SITTING 7+ MONTHS ON A SHELF WHILE GW BORE THE BSE MRR POLICY, i.e. legal trading of all strains of TSE. now understand, i confirmed this case 7 months earlier to the TAHC, and then, only after i contacted the Honorable Phyllis Fong and after an act of Congress, this animal was finally confirmed ;

    During the course of the investigation, USDA removed and tested a total of 67 animals of interest from the farm where the index animal’s herd originated. All of these animals tested negative for BSE. 200 adult animals of interest were determined to have left the index farm. Of these 200, APHIS officials determined that 143 had gone to slaughter, two were found alive (one was determined not to be of interest because of its age and the other tested negative), 34 are presumed dead, one is known dead and 20 have been classified as untraceable. In addition to the adult animals, APHIS was looking for two calves born to the index animal. Due to record keeping and identification issues, APHIS had to trace 213 calves. Of these 213 calves, 208 entered feeding and slaughter channels, four are presumed to have entered feeding and slaughter channels and one calf was untraceable.

    http://www.usda.gov/wps/portal/!ut/p/_s.7_0_A/7_0_1OB?contentidonly=true&contentid=2005/08/0336.xml

    Executive Summary In June 2005, an inconclusive bovine spongiform encephalopathy (BSE) sample from November 2004, that had originally been classified as negative on the immunohistochemistry test, was confirmed positive on SAF immunoblot (Western blot). The U.S. Department of Agriculture (USDA) identified the herd of origin for the index cow in Texas; that identification was confirmed by DNA analysis. USDA, in close cooperation with the Texas Animal Health Commission (TAHC), established an incident command post (ICP) and began response activities according to USDA’s BSE Response Plan of September 2004. Response personnel removed at-risk cattle and cattle of interest (COI) from the index herd, euthanized them, and tested them for BSE; all were negative. USDA and the State extensively traced all at-risk cattle and COI that left the index herd. The majority of these animals entered rendering and/or slaughter channels well before the investigation began. USDA’s response to the Texas finding was thorough and effective.

    snip…

    Trace Herd 3 The owner of Trace Herd 3 was identified as possibly having received an animal of interest. The herd was placed under hold order on 7/27/05. The herd inventory was conducted on 7/28/05. The animal of interest was not present within the herd, and the hold order was released on 7/28/05. The person who thought he sold the animal to the owner of Trace Herd 3 had no records and could not remember who else he might have sold the cow to. Additionally, a search of GDB for all cattle sold through the markets by that individual did not result in a match to the animal of interest. The animal of interest traced to this herd was classified as untraceable because all leads were exhausted.

    Trace Herd 4 The owner of Trace Herd 4 was identified as having received one of the COI through an order buyer. Trace Herd 4 was placed under hold order on 7/29/05. A complete herd inventory was conducted on 8/22/05 and 8/23/05. There were 233 head of cattle that were examined individually by both State and Federal personnel for all man-made identification and brands. The animal of interest was not present within the herd. Several animals were reported to have died in the herd sometime after they arrived on the premises in April 2005. A final search of GDB records yielded no further results on the eartag of interest at either subsequent market sale or slaughter. With all leads having been exhausted, this animal of interest has been classified as untraceable. The hold order on Trace Herd 4 was released on 8/23/05.

    Trace Herd 5 The owner of Trace Herd 5 was identified as having received two COI and was placed under hold order on 8/1/05. Trace Herd 5 is made up of 67 head of cattle in multiple pastures. During the course of the herd inventory, the owner located records that indicated that one of the COI, a known birth cohort, had been sold to Trace Herd 8 where she was subsequently found alive. Upon completion of the herd inventory, the other animal of interest was not found within the herd. A GDB search of all recorded herd tests conducted on Trace Herd 5 and all market sales by the owner failed to locate the identification tag of the animal of interest and she was subsequently classified as untraceable due to all leads having been exhausted. The hold order on Trace Herd 5 was released on 8/8/05.

    Trace Herd 6 The owner of Trace Herd 6 was identified as possibly having received an animal of interest and was placed under hold order on 8/1/05. This herd is made up of 58 head of cattle on two pastures. A herd inventory was conducted and the animal of interest was not present within the herd. The owner of Trace Herd 6 had very limited records and was unable to provide further information on where the cow might have gone after he purchased her from the livestock market. A search of GDB for all cattle sold through the markets by that individual did not result in a match to the animal of interest. Additionally, many of the animals presented for sale by the owner of the herd had been re-tagged at the market effectually losing the traceability of the history of that animal prior to re-tagging. The animal of interest traced to this herd was classified as untraceable due to all leads having been exhausted. The hold order on Trace Herd 6 was released on 8/3/05.

    Trace Herd 7 The owner of Trace Herd 7 was identified as having received an animal of interest and was placed under hold order on 8/1/05. Trace Herd 7 contains 487 head of cattle on multiple pastures in multiple parts of the State, including a unit kept on an island. The island location is a particularly rough place to keep cattle and the owner claimed to have lost 22 head on the island in 2004 due to liver flukes. Upon completion of the herd inventory, the animal of interest was not found present within Trace Herd 7. A GDB search of all recorded herd tests conducted on Trace Herd 7 and all market sales by the owner failed to locate the identification tag of the animal of interest. The cow was subsequently classified as untraceable. It is quite possible though that she may have died within the herd, especially if she belonged to the island unit. The hold order on Trace Herd 7 was released on 8/8/05.

    http://www.aphis.usda.gov/lpa/issues/bse/epi-updates/bse_final_epidemiology_report.pdf

    THE SECRET MAD COW POSITIVE TEST, THAT WAS COVERED UP

    Owner and Corporation Plead Guilty to Defrauding Bovine Spongiform Encephalopathy (BSE) Surveillance Program

    An Arizona meat processing company and its owner pled guilty in February 2007 to charges of theft of Government funds, mail fraud, and wire fraud. The owner and his company defrauded the BSE Surveillance Program when they falsified BSE Surveillance Data Collection Forms and then submitted payment requests to USDA for the services. In addition to the targeted sample population (those cattle that were more than 30 months old or had other risk factors for BSE), the owner submitted to USDA, or caused to be submitted, BSE obex (brain stem) samples from healthy USDA-inspected cattle. As a result, the owner fraudulently received approximately $390,000. Sentencing is scheduled for May 2007.

    snip…

    4 USDA OIG SEMIANNUAL REPORT TO CONGRESS FY 2007 1st Half

    http://www.usda.gov/oig/webdocs/sarc070619.pdf

    PAUL BROWN COMMENT TO ME ON THIS ISSUE

    Tuesday, September 12, 2006 11:10 AM

    “Actually, Terry, I have been critical of the USDA handling of the mad cow issue for some years, and with Linda Detwiler and others sent lengthy detailed critiques and recommendations to both the USDA and the Canadian Food Agency.”

    end…tss

    Saturday, May 26, 2012

    Are USDA assurances on mad cow case ‘gross oversimplification’?

    SNIP…

    What irks many scientists is the USDA’s April 25 statement that the rare disease is “not generally associated with an animal consuming infected feed.”

    The USDA’s conclusion is a “gross oversimplification,” said Dr. Paul Brown, one of the world’s experts on this type of disease who retired recently from the National Institutes of Health. “(The agency) has no foundation on which to base that statement.”

    “We can’t say it’s not feed related,” agreed Dr. Linda Detwiler, an official with the USDA during the Clinton Administration now at Mississippi State.

    In the May 1 email to me, USDA’s Cole backed off a bit. “No one knows the origins of atypical cases of BSE,” she said

    The argument about feed is critical because if feed is the cause, not a spontaneous mutation, the California cow could be part of a larger outbreak.

    SNIP…

    http://bseusa.blogspot.com/2012/05/are-usda-assurances-on-mad-cow-case.html

    Saturday, August 4, 2012

    *** Final Feed Investigation Summary – California BSE Case – July 2012 (ATYPICAL L-TYPE BASE BSE)

    http://transmissiblespongiformencephalopathy.blogspot.com/2012/08/final-feed-investigation-summary.html

    in the url that follows, I have posted

    SRM breaches first, as late as 2011.

    then

    MAD COW FEED BAN BREACHES AND TONNAGES OF MAD COW FEED IN COMMERCE up until 2007, when they ceased posting them.

    then,

    MAD COW SURVEILLANCE BREACHES.

    Friday, May 18, 2012

    Update from APHIS Regarding a Detection of Bovine Spongiform Encephalopathy (BSE) in the United States Friday May 18, 2012

    http://transmissiblespongiformencephalopathy.blogspot.com/2012/05/update-from-aphis-regarding-detection.html

    2009 UPDATE ON ALABAMA AND TEXAS MAD COWS 2005 and 2006

    http://bse-atypical.blogspot.com/2006/08/bse-atypical-texas-and-alabama-update.html

    http://madcowtesting.blogspot.com/2007/10/bse-base-mad-cow-testing-texas-usa-and.html

    http://madcowtesting.blogspot.com/

    Sunday, May 18, 2014

    *** Chronic Wasting Disease CWD TSE PRION DISEASE and the transmission to other species

    http://chronic-wasting-disease.blogspot.com/2014/05/chronic-wasting-disease-cwd-tse-prion.html

    Sunday, August 09, 2009

    CJD…Straight talk with…James Ironside…and…Terry Singeltary… 2009

    http://creutzfeldt-jakob-disease.blogspot.com/2009/08/cjdstraight-talk-withjames.html

    http://prionopathy.blogspot.com/2011/05/variably-protease-sensitive-prionopathy.html

    http://cjdusa.blogspot.com/

    Subject: Re: Hello Dr. Gibbs………..

    Date: Wed, 29 Nov 2000 14:14:18 –0500

    From: “Clarence J. Gibbs, Jr., Ph.D.”

    To: “Terry S. Singeltary Sr.” References:

    Hi Terry:

    326 E Stret N.E., Washington, D. C. 20002.

    Better shrimp and oysters than cards!!!!

    Have a happy holiday and thanks for all the information you bring to the screen.

    Joe Gibbs ==========

    Tuesday, August 18, 2009

    * BSE-The Untold Story – joe gibbs and singeltary 1999 – 2009

    http://madcowusda.blogspot.com/2009/08/bse-untold-story-joe-gibbs-and.html

    CJD QUESTIONNAIRE USA

    http://cjdquestionnaire.blogspot.com/2007/11/cjd-questionnaire.html

    http://cjdquestionnaire.blogspot.com/

    CJD and Baby foods (the great debate 1999)

    Subject: Re: Girl, 13, shows CJD symptoms.

    From: “Terry S. Singeltary Sr.”

    Reply-To: Bovine Spongiform Encephalopathy

    Date: Wed, 24 Nov 1999 11:35:44 -0600 Content-Type: text/plain Parts/Attachments: text/plain (67 lines)

    http://bseinquiry.blogspot.com/2008/05/bse-cjd-and-baby-foods-great-debate.html

    Sunday, May 18, 2008

    MAD COW DISEASE BSE CJD CHILDREN VACCINES

    http://bseinquiry.blogspot.com/2008/05/mad-cow-disease-bse-cjd-children.html

    Sunday, May 18, 2008

    BSE Inquiry DRAFT FACTUAL ACCOUNTS DFAs

    http://bseinquiry.blogspot.com/2008/05/bse-inquiry-draft-factual-account-dfa.html

    Monday, May 19, 2008

    *** SPORADIC CJD IN FARMERS, FARMERS WIVES, FROM FARMS WITH BSE HERD AND ABATTOIRS ***

    http://bseinquiry.blogspot.com/2008/05/sporadic-cjd-in-farmers-farmers-wives.html

    *** U.S.A. 50 STATE BSE MAD COW CONFERENCE CALL Jan. 9, 2001

    http://tseac.blogspot.com/2011/02/usa-50-state-bse-mad-cow-conference.html

    http://madcowusda.blogspot.com/2012/02/eight-former-secretaries-of-agriculture.html

    Monday, May 05, 2014

    Member Country details for listing OIE CWD 2013 against the criteria of Article 1.2.2., the Code Commission recommends consideration for listing

    http://chronic-wasting-disease.blogspot.com/2014/05/member-country-details-for-listing-oie.html

    Tuesday, April 01, 2014

    Questions linger in U.S. CJD cases 2005, and still do in 2014

    http://creutzfeldt-jakob-disease.blogspot.com/2014/04/questions-linger-in-us-cjd-cases-2005.html

    Friday, April 25, 2014

    Accuracy of administrative diagnostic data for pathologically confirmed cases of Creutzfeldt-Jakob disease

    http://creutzfeldt-jakob-disease.blogspot.com/2014/04/accuracy-of-administrative-diagnostic.html

    Sunday, April 06, 2014

    SPORADIC CJD and the potential for zoonotic transmission there from, either directly or indirectly via friendly fire iatrogenic mode, evidence to date

    http://creutzfeldt-jakob-disease.blogspot.com/2014/04/sporadic-cjd-and-potential-for-zoonotic.html

    TSS

    Monday, June 02, 2014

    Confirmed Variant CJD Case in Texas

    http://vcjd.blogspot.com/2014/06/confirmed-variant-cjd-case-in-texas.html

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